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The closed loop responses are tested through dynamic simulations with the obtained models when different meals intake and insulin dosages are given to the patient Nº 5004 from the Center of Diabetes Technology (UVa/USA).
The FFAs levels were similar among NW and OO men, both at fasting and after HC and NC meals intake and 5(b)).
While comparing the insulin levels between NW and OO men, the OO men from group I had significantly higher insulin levels both at fasting state and after HC and NC meals intake).
As a part of this study, the FFAs levels were evaluated and it was observed that in NW men, as well as in OO men, FFAs levels were significantly higher after NC and HF meals intake, in comparison to HC meal.
Furthermore, the AUCs for insulin levels after HC and NC meals intake were significantly higher in OO than in NW men (after HC meal 21999 ± 2917 versus 11047 ± 2162, resp., P < 0.01; and after NC meal 12845 ± 1712 versus 5694 ± 716, resp., P < 0.01).
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The size of portions offered did, however, influence meal intake (P < 0.0001).
In normal-weight and obese individuals, intranasal oxytocin acutely limits meal intake and the consumption of palatable snacks.
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