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MBC describes the optimal model obtained by clustering the proteins in the first (s1) and second (s2) step (number of clusters between parentheses).
Firstly, due to the absence of patient level empirical comparative study covering a time span consistent with the assumed survival horizon for MBC patients, the Markov model extrapolated estimates for 5-year OS and PFS, as well as costs for both nab-paclitaxel and conventional paclitaxel from the results of a pivotal comparative trial.
We further use neurite orientation dispersion and density imaging (NODDI) to show that more goal-directed model-based learning (MBc) is also associated with higher mOFC neurite density and habitual model-free learning (MFc) implicates neurite complexity in the putamen.
Microbial biomass C (MBC) and ratio of MBC to soil organic C (SOC) (MBC/SOC) were higher in M1 and M2 than in CK in 2007 growing season.
This model yields the MBC IRR for each group of the 5-group indicator, compared with the reference group (<40 per 100 000 woman-years).
For efficient design of automotive engines, mathematical models for automotive engines are created in MBC, and statistics and optimization are applied to the model by using MBC software, such as [10].
All literature thus far supports a model whereby the Mbc-ELMO complex activates Rac.
We adopted a model-based clustering (MBC) procedure using the R package mclust [ 30- 32].
The main contribution of this paper is the development and verification of a predictive mathematical model of high-pressure MBC for natural gas sweetening applications, based on which model-based parametric analysis and optimization can be conducted.
These clinical results were recently replicated in a preclinical model of postsurgical advanced MBC (Guerin et al, 2013).
The aim of this project was to perform simulations to determine which capecitabine dose would be noninferior to the registered dose in combination with docetaxel in the second-line treatment of MBC using a previously developed and extended modeling framework.
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