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Indeed, given the relatively early character of endolysosomal/dysfunction in AD, and a major reliance of amyloidogenic processing on sorting regulators, future therapeutic efforts should maybe aim to lengthen the fidelity of endosomal transport and degradation, and not only focused on majorly targeting the amyloidogenic enzymes, BACE1 and γ-secretase complexes.
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Now that everybody is thinking green, maybe Kumho Tire USA could aim to add a feature to its car tire that smells like lavender ("Sweet Smell of Sidewalls," The Goods, Feb. 11).
"Maybe I should aim to be admitted into a community hospital," my dad sneered once.
Blatt's jacket bio cites "his fun approach to data journalism"—a bit of prolepsis, maybe, aimed at those of us who'd sooner watch paint dry than look at anything quantitatively and his book is laden with charts, lists, and tables printed in a gentle purple.
I think Holly Smale could have made it more improved and better and maybe aimed at an older audience if she had wanted too.
Others aim to be.
"We aim to entertain".
Both aim to leave Tuesday.
"We aim to destroy it.
I aim to do that".
"We aim to get perfect".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com