In sum, our findings suggest mechanisms that may underlie adolescents' vulnerability to poor decision-making and risk-taking behavior.
We reasoned that shared deficits across the two conditions may reflect underlying vulnerability mechanisms, whereas impairments specific to alcohol dependence may reflect cumulative effects of alcohol consumption.
Conclusions: Interpersonal impairment is a stable feature of depression, a significant challenge to treatment, and may reflect underlying vulnerability to the onset, and recurrence, of depressive experiences.
This transient sex difference may help to define the cellular and circuit mechanisms that underlie vulnerability to attention deficit disorder.
Individual variation in behavioral coping strategies to stress implies that animals may have a distinct physiological adaptation to stress; these differences may underlie differences in vulnerability to stress-related diseases.
This peculiar indifference of EC astrocytes to the AD-specific lesion may underlie the particular vulnerability of the EC to the AD-like pathology and provide an explanation of why EC is the first brain region to be affected in the course of AD.
The P479L variant may represent an underlying vulnerability (i.e. a predisposition to hypoglycemia) that, when combined with exogenous stressors during a critical development period and/or intercurrent illness, may increase risk for unexpected infant death.
Whatever fears, whatever sense of vulnerability may underlie such behavior, it also comes out of entitlement, the entitlement to inflict suffering and even death on other people.
Individual differences in the operation of this threat-processing system may underlie individual differences in vulnerability to anxiety and anxiety disorders (Davis and Whalen, 2001).
Compelling evidence suggests that biological sex differences in the NSDA pathway may underlie these differences in vulnerability, and could also account for the sexually dimorphic actions of estradiol, which protects females against striatal DA loss in experimental PD, but fails to protect, or may even worsen, striatal lesions in males.
