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This mechanism may underlie effects of dynorphins under pathological conditions including chronic pain and tissue injury.
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There is concern that pharmacogenomics GWAS themselves are susceptible to many limitations: insufficient sample size, selection biases for genetic variants, environmental interactions that may affect the outcome measures and multiple gene gene interactions that may underlie unexplained effects (Motsinger-Reif et al., 2010).
A gene responsible for a liver enzyme may underlie side effects sometimes seen with Seldane, Hoechst Marion Roussel's allergy drug.
Neural regulation of stress responses, and the feedback of stress hormones to the brain, reflect complex brain body interactions that may underlie the effects of psychological stress on health.
Numerous molecular mechanisms may underlie the effects of dietary fatty acids on parameters of health.
These activations may underlie the effects of reward on accuracy and RTs in the number comparison task in predictable blocks.
Cell functional abnormalities such as suboptimal expression of signalling molecules or genes necessary for cell cycle progression, or abnormalities with energy supply and utilisation may underlie these effects.
These results suggest that the anatomical localization of iron may underlie the effects of maternal TURP and/or iron supplementation to modulate striatal DA transmission, as opposed to cortical DA function, although it does not fully explain the differential effect between NAcc and dSTR.
The genome-wide gene expression profiles determined on Affymetrix microarrays were analysed to detect potential cis-acting elements which may underlie the effects of alcohol.
It appears that activation of JAK3, EGFR, Src kinase, and MAP kinase signaling cascades may underlie these effects (Eum et al. 2004, 2006).
This study applied toxicogenomics-based analyses to air chemistry research to reveal potential biological mechanisms that may underlie health effects induced by air mixtures.
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