Because these changes occur in the primary region of thalamocortical input, they may underlie specific alterations in the processing of visual information both cortically and subcortically during periods of dark rearing and light exposure.
The sustained adaptations in the NF-κB system apparently represent a shift to new steady state or allostatic levels in the NF-κB/p50 activities that may underlie persistent alterations in expression of their target genes.
Accordingly, despite their overlapping symptomatology, there is accumulating evidence that apathy and anhedonia may have different underlying alterations in brain circuits [ 3, 39].
Such alterations may underlie an increased susceptibility of AIDS patients to mycobacterial infections, namely by Mycobacterium avium.
Aberrant central regulation of a spontaneous or evoked sympathetic surge may underlie the reversible vascular alterations of RCVS.
Together with previous data, we propose that different combinations of genetic alterations may underlie different morphological types of colorectal cancer.
A decline in hippocampal neurogenesis occurs with age and may underlie cognitive and mood alterations associated with aging and Alzheimer's disease (Lazarov et al., 2010; Mu and Gage, 2011).
Future research is particularly challenged to elucidate the specific molecular and cellular mechanisms that may underlie the observed learning-induced alterations in brain structure.
These events may underlie hepatocellular steatosis and associated alterations in lipid metabolism, diabetes mellitus and insulin resistance [ 3].
Current analysis of cancer genome sequencing has revealed disease processes and genomic alterations that may underlie disease initiation or evolution (Nik-Zainal et al. 2012, Baca et al. 2013, Tarpey et al. 2013).
