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The known CB1 ligands are highly diverse structurally, so CB1 receptor may undergo considerable conformational changes to accept different ligands, which is challenging for molecular docking methods.
During the two-fluoroscopic technique, however, the operator or patient may undergo considerable radiation exposure.
The quantification of gene gain and loss suggests that both have been extensive in the evolutionary history of the P. syringae species complex and that the genomes of these pathovars may undergo considerable fluctuation even over relatively short evolutionary time periods.
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Therefore, it is important to consider that evolutionarily related toxins may only share weak sequence similarity and may have undergone considerable structural rearrangements.
Thus many lawmakers say it is likely to undergo considerable revision.
These DNA segments undergo considerable rearrangements, resulting in the synthesis of a great variety of antibodies.
Their acyl chains now undergo considerable motion, leading to transiently kinked conformations.
Iron and steel surfaces deployed in service in these environments undergo considerable corrosion.
Insects undergo considerable change in form during the pupal stage, and emerge as adults.
Relatives of patients in the ICU undergo considerable stress.
It is indeed possible that the population sizes of individual clones undergo considerable fluctuations.
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