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Also, proteins may undergo conformation change and functionality missing upon association with NPs [14, 15].
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In the modeled structure, the finger domains from two Get3 monomers collide with each other (data not shown), suggesting that the Get3 finger domains may undergo conformational changes when the Get3 dimer switches from the open to the closed conformation.
Once the antimicrobial peptide binds to the cell membrane of a pathogenic microbe, it may undergo significant conformational change and adopt a specific conformation, such as a α-helix.
Segments of DNA where the bases have been chemically modified by methylation may undergo a larger change in conformation and adopt the Z form.
This finding suggests that the SM proteins may undergo a transition from a conformation suitable for binding to a single SNARE protein called syntaxin, to one that interacts with SNARE complexes an idea previously suggested for other SM proteins (for example, see Christie et al., 2012).
The conformation of the Thr286 containing motif may undergo significant changes upon binding of NR2B similar to what was reported earlier for Ca2+/calmodulin binding [27].
Previous studies have revealed that specific backbone conformations are likely to be a part of ligand-binding site and that the magnitude of dihedral angles may undergo slight changes after ligand binding [ 13, 15, 19]; however, no method has considered the conformation of amino acids in ligand-binding site prediction.
In addition, Kv channels may undergo cycles of plasma membrane trafficking and internalization, a process that may require features of the natural conformation that is lost following truncation and/or GFP insertion.
These then may undergo further reactions.
The Greens may undergo similar moderation.
He may undergo a magnetic resonance imaging test on Tuesday.
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