Sentence examples for may ultimately underlie from inspiring English sources

This specific subcellular localization may ultimately underlie the regulation of isoform-specific functions.

While genetic and molecular heterogeneity may ultimately underlie the different responses to therapy observed among patients with AML, there appears to be a finite number of intracellular signaling pathways through which these differences are expressed.

Even though such differences at tissue level cannot be captured by the analysis of blood or plasma data, pharmacodynamic variants may ultimately underlie differences in response rates.

These studies have led to the hypothesis that in many types of cancers, including breast cancer, distinct progenitors and their abrogated self-renewal pathways may ultimately underlie the mechanisms of heterogeneity observed among subtypes of human breast cancer [ 33].

Enhanced concentration, interneuronal transmission and aggregation of α-syn could set up a self-perpetuating loop that, fueled by the generation of toxic protein fibrils, may ultimately underlie the progression of α-syn pathology and neurodegenerative cascade in PD.

Similarly, the cellular movement and immune cell trafficking networks involves TNF (Entrez Gene: 7124) and IFNG (Entrez Gene: 3458) as hub genes in Family 1 and IGF1R (Entrez Gene: 3480) and EGFR (Entrez Gene: 1956) as hub genes in Family 2. The results may argue that networks rather than genes may ultimately underlie the etiology of schizophrenia and related disorders.

These complex relationships, which we have illustrated in our study findings, may ultimately help to explain the mechanisms underlying how innovations come to be sustained.

A better understanding of the underlying neuroimmunological mechanisms may ultimately pave the way for more effective and safer therapies harnessing adaptive immunity to treat cerebral β-amyloidosis.

If this appears to be a canonical response, this may ultimately help in identifying signaling pathways underlying the organismal response to heat shock in particular or stress in general that lead to perturbations in recombination frequency.

The system, when fully optimized, may incorporate high throughput gene expression profiles as well as new drug-related research information to impact the underlying cause for drug sensitivities, and may ultimately provide physicians with guidelines for prescriptions.

This provides a better insight into the mechanisms underlying the hypoxic response in STS and may ultimately yield information on novel prognostic and predictive markers or targets for treatment.