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Taken together, we propose that DST-primed, hyperproliferative CD4+ T-cells represent a precursor population that may ultimately develop into fully functional Tregs (CD4+CD45RC−Foxp3+) in the presence of alloantigens expressed by the liver graft (Fig. 2, 4 and 6A).
Consequently, it has been hypothesized that sCLU gene silencing using siRNA or other techniques may ultimately develop into attractive antitumor apoptotic induction [ 294].
While surgical excision may be curative in greater than 90% of patients with thin melanomas (T1 lesions), there is a subset of patients who may ultimately develop aggressive clinical behavior.
The majority of patients will be diagnosed with early stage disease [ 3], which is amenable to curative treatment with surgical care and/or radiation [ 4]; however, 6 10 % of patients will present with metastatic breast cancer [ 5], and up to 30%% of all patients may ultimately develop metastatic disease [ 6].
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If supported by further research, these results may ultimately help develop intervention programs that could prevent long-term pain in disability in children and adolescents.
With this, the study may ultimately help develop policies and guidelines on nurse uniform wearing practices.
Hybrid may ultimately mean developing for multiple platforms, rather than trying to integrate everything.
We anticipate that this new biomarker will create better opportunities to individualize therapy and may ultimately be developed as a novel molecular target.
Taken together, these results demonstrate that single molecule force measurement allows us to quantify the elastic and thermodynamic properties of biological macromolecules, and the technique may ultimately be developed into a tool for drug screening.
Further investigations of the involved pathways in NSCLC cells and tissues are warranted to elucidate the molecular mechanisms of NSCLC growth and may ultimately help developing an effective therapeutic strategy for treating this cancer.
As the acute infection wanes individuals may remain asymptomatic; however, 10 to 30% of infected individuals ultimately develop chronic cardiomyopathy [7].
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