There are conceivably two potential pathways through which a neighborhood environment might influence a girl's pubertal timing: (1) through reduced access to healthful foods and physical activity, which may lead to overweight and, in turn, earlier pubertal onset, and (2) through exposure to acute and chronic stress, which may trigger hormonal stress responses that prompt pubertal onset.
Water stress may trigger different stress-responsive gene expression in different tissues at the same developmental stage or in the same tissue at different developmental stages.
This change may trigger metabolic stress and enhances a strong stress response.
For biologics, a change in the manufacturing process may trigger certain stress stability studies to verify if there is any change to the drug degradation profile.
Mg deficiency may be exacerbated by low Mg with high or low Ca intakes [ 13, 28], which may trigger inflammatory stress, contributing to the development of CVD [ 13].
Our study indicates that short-term exposure to DEE may trigger rapid stress responses and CYP1A1 induction in specific brain regions, most notably in the pituitary.
Alternatively, as described in β cells, palmitate can lead to an early and sustained depletion of ER Ca2+ stores, which may trigger ER stress via impaired protein folding [ 41].
Controlled inhalation studies in mice have confirmed that ambient PM and nanoparticles may trigger oxidative stress, toxicity, and inflammation in brain tissue (Campbell et al. 2005; Elder et al. 2006; Kleinman et al. 2008; Veronesi et al. 2005).
Thus, oncogene-mediated hyperplasia may trigger a stress-mediated stromal reaction that initiates a vicious cycle promoting tumour invasion.
This is the first study in humans to investigate longitudinally, whether in humans, the effect of maternal perinatal emotional symptoms such as stress, anxiety and depression that may trigger a biological stress response on age at first seizure occurrence.
