Sentence examples for may trigger neuronal from inspiring English sources

Recent in vitro data suggest that giving glucose boluses after hypoglycaemia may trigger neuronal death due to ROS overproduction [ 125].

Thus, GA may trigger neuronal damage partially through apoptotic pathway and via activation of NMDA receptors in cultured primary striatal neurons.

These findings have led to the hypothesis that amyloid-β (Aβ), the peptide derived from APP and widely believed to play a critical role in AD pathogenesis, may trigger neuronal hyperexcitability, seizures, and ultimately worsen neuronal dysfunction in AD.

Moreover, other unknown death pathways may also trigger neuronal apoptosis.

This suggests that the transcriptional up-regulation of the bim gene may not be sufficient to trigger neuronal death.

When post-mitotic neurons try to re-enter the cell cycle, the very attempt to transcribe a subset of cell cycle-related genes that have not been transcribed for years in the lifetime of a mature neuron may accumulate damaged DNA, which could trigger neuronal apoptosis [ 59].

Aberrant activation of Drp1 is thought to trigger neuronal apoptosis in several neurodegenerative diseases, including Huntington's disease and Alzheimer's disease, and may be related to the mitochondrial release of the pro-apoptotic molecule Bax [ 14, 25].

It is tempting to speculate that gliosis in the wobbler spinal cord, the local accumulation of astrocyte cell bodies, and high density of astrocytic processes may interfere with the diffusion of neuroactive substances in gliotic tissue, some of which are neurotoxic, and cooperate or even trigger neuronal death.

Our results indicate that subanesthetic concentration of sevoflurane can trigger neuronal apoptosis in the postnatal mouse brain.

A metabolite of sAPP-β interacts with DR6 to trigger neuronal death [29].

However, uncontrolled and sustained secretion of inflammatory cytokines by microglia also trigger neuronal cell death [ 4].