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Defensome assembles several signaling proteins together so that they may trigger immune responses quickly and efficiently.
Our study shows that RB cells may trigger immune responses by reducing IL-10 production, in addition to increasing IL-12 secretion by DCs.
Now researchers report in tomorrow's issue of Science that some people develop the persistent condition because the infection may trigger immune cells to attack both the spirochete protein and a protein found on human cells.
AIDS researchers speculate that the vaccine may trigger immune killer cells to destroy HIV-infected cells or stimulate production of immune-system messengers called chemokines that can block a receptor used by SIV to enter cells and establish an infection.
Although such findings are encouraging, for clinical translation all cell-based therapeutic agents would need to be free of animal-derived cells or materials because of concerns about possible transfer of pathogens or xenogens, which may trigger immune reactions in human subjects.
This may trigger immune overactivation and subsequently tumorigenesis.
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Therefore, FAK inhibitors may trigger immune-mediated tumor regression, providing previously unrecognized therapeutic opportunities.
Moreover, increased radiation injury with the 18 Gy treatments may trigger immune-mediated damage of healthy nervous tissue.
An aberrant intestinal T lymphocyte homing to the liver may contribute to trigger immune hepatic damage [ 55].
Some researchers have suggested that the cells may trigger an immune reaction that mistakenly attacks the child's own cells as well, resulting in auto-immune diseases such as type-1 diabetes.
If harmful bacteria manage to slip past those defenses, they may trigger an immune reaction that is sensed by the mother, prompting her to go into labor.
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