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The data suggested that the local environment created within nasal polyp tissue may trigger formation of ectopic follicular structures with AID expression/activity and consequently initiate CSR.
Further the S. pombe WISH/DIP/SPIN90 ortholog Dip1 (Ldb17 in S. cerevisiae) binds Arp2/3 complex and stimulates unbranched nucleation, suggesting that in vivo it may trigger formation by Arp2/3 complex of the first mother filament to initiate actin network assembly, a model that is strongly supported by analysis of its mutant phenotype (Basu and Chang 2011).
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It is debated whether chronic urogenital inflammations and infections may trigger the formation of antisperm antibodies (ASA) in semen.
Another common pitfall is to perform the time-kill assay when the culture is too close to the next stationary phase, which again may trigger the formation of persister cells.
In this way, the substrate loading on the periplasmic side may trigger the formation of the ATPase catalytic site in the cytosolic NBD dimer, and subsequently cause a COut-to-CIn conformational change (Fig. 1C).
This is consistent with the fact that free extracellular DNA itself may trigger biofilm formation [17].
Alternatively, the binding may trigger the formation of translationally repressed RNPs.
A critical combination of components at such hotspots may trigger neocentreomere formation, the mechanisms of which are still unresolved.
Mycobacterium tuberculosis surface antigens may trigger the formation of cross-reactive antibodies against aquaporin-4 channel proteins.
Low transcriptional induction may be able to trigger formation of a mating projection but not sufficient to induce this transcriptional negative feedback resulting in only a single projection, e.g. AI-Ste5p (Figures 2 and 7C).
The elevated electron abundance facilitates the formation of H2 and HD, which may trigger secondary Population III star formation once the gas recollapses.
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