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The mechanisms include increased Th-2 cells with reduction in pro-inflammatory circulating cytokines or externalisation of phosphatidylserine, which may trigger cellular apoptosis, in particular of CD4+ cells [33].
Critically shortened telomeres may trigger cellular senescence and apoptosis.
Helicobacter pylori infections have been linked to peripheral neuropathies as they may trigger cellular and humoral immunity due to the sharing of similar epitopes present in the nervous tissue.
As lysosomal permeability is accompanied by the release of cathepsins into cytosol where they may trigger cellular response, including autophagy, we measured enzymatic activity of acidic phosphatases in both whole-cell extracts and lysosomal fractions.
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Depending on the nature of the epitope and type of cell, the aggregation of epitopes on the target cell may also trigger cellular responses [5], [6].
It is possible that antibody-mediated direct inhibition of Dsg binding may contribute to trigger cellular signalling events (Muller et al. 2008a; Sharma et al. 2007; Tsunoda et al. 2003).
They even have some inkling as to the "how" of ageing, the biochemical processes which may trigger these cellular phenomena.
It is clear that even a brief ischemic stroke may trigger complex cellular events that ultimately lead to the neuronal cell death and loss of neuronal function [1, 4, 5].
This suggests that compound 1 may trigger additional cellular events which positively contribute to the antibacterial activity.
Several factors may trigger apoptosis: cellular damage, infection with a virus and homeostasis.
Moreover, signals from the extracellular environment may trigger different cellular priorities and objectives.
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