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This approach involves the mtDNA from a third individual thereby may trigger both ethical and technical conflicts.
Whilst DNA repair and genomic instability may, or may not, be directly inter-linked, FOXM1B induction may trigger both DNA repair (aberrant repair) as well as genomic instability.
This study highlights the paradoxical simultaneous loss and gain of bone in a mouse model of AS and suggests that BMPs may trigger both inflammation and ankylosis.
It is suggested that TRPV4-mediated [Ca2+]i rise in endothelial cells may trigger both NO- and/or EDHF-dependent vasodilatation that seems to be vascular bed-dependent.
Certain cultural changes such as an increase in the value placed on investment in child human capital, may trigger both mortality and fertility declines, given the growing evidence pointing to the influential role of conditions in early childhood in determining adult health and human capital.
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Therefore, our data on GES-treated animals indicate that taurine deficiency may indeed trigger both photoreceptor and retinal ganglion cell degeneration.
Thus, increasing severity of illness may have triggered both room transfers to provide a higher level of care or an isolation room, and may have resulted in delirium, in some of the patients studied.
Additionally, ROS may trigger activation of both nuclear factor-κB and FOXO signaling pathways, resulting in protein loss, possibly through the ubiquitin-proteasome pathway [ 40].
While the long-term effects of subtle hypoxia on brain tissue are not fully understood, it is becoming increasingly clear that oxidative stress may trigger neuropathological processes both local and distal to the site of mild brain contusion, effects which may only manifest themselves months to years later [ 31].
It has been shown that heart failure may trigger catecholamine desensitization to both isoproterenol and norepinephrine in the presence and absence of ganglionic blockade [37].
For instance, temperature and light intensity during larval development are environmental cues that may trigger phenotypic shifts in both larvae and adults (e.g. Simpson et al. 2011).
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CEO of Professional Science Editing for Scientists @ prosciediting.com