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Although the link between reduced phospholamban expression and altered cardiac contractile function in APP/PS1 hearts is unclear, reduced phospholamban levels may trigger altered intracellular Ca2+ homeostasis en route to affect cardiomyocyte contractile function [18].
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These results indicate that cone loss may be attributed, at least partially, to impaired protein folding and deficient targeting triggering altered photoreceptor physiology and intracellular death cascade.
The need to select only hospitals staffed by specialists would have improved the accuracy and uniformity of the diagnosis of IBD, especially because bowel infections are common in countries such as ours, and may trigger and alter the course of underlying IBD [ 21, 22].
Such altered states may trigger a transcriptional response towards preserving reductant and/or ATP at the expense of glutamine and glutamate production using this GS-GOGAT system.
This altered lipid composition may trigger a more rapid inflammation leading to atopic lesions in contrast to body sites that are not predisposed to AD lesions.
The cardiovascular adaptation to psychological stress seems physiological, but the altered autonomic input may trigger ventricular arrhythmias in the presence of heart disease [ 8, 9].
Some formula milk may also have altered protein content that may trigger allergic reactions.
7, 8 Insults, such as TBI, may trigger a sequence of neurobiological events that alter that trajectory, prematurely causing brain atrophy, and potentially manifesting as an early onset of neurodegeneration.
But as more is learned and circumstances change, these elements may trigger further changes in technology, user practice, infrastructure, and policies, eventually altering the basic architecture of the regime.
Besides these direct effects of oxidative injury, there can be indirect injury because the nicks and breaks in DNA strands can trigger activation of Poly(ADP) polymerase (PARP), which alters gene expression, DNA replication and may trigger apoptosis.
Environmental disturbance regimes are more frequently being altered by historically novel events and disturbance interactions, which may trigger reorganizations of new ecosystem states and processes.
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CEO of Professional Science Editing for Scientists @ prosciediting.com