Sentence examples for may tolerate mutations from inspiring English sources

Mutations conferring resistance to antibiotics target essential genes which may tolerate mutations poorly.

Purifying selection may tolerate mutations constrained by protein structure only after certain neighboring mutations have occurred.

Each subunit may tolerate mutations differentially because of the mutation position, protein function, and presence of compensatory mutations in other sites.

Though speculative, it is possible that strong promoters may be able to tolerate mutations that result in moderately reduced or increased activity, because their transcriptional activity would still be sufficient to maintain functional expression levels.

In contrast, weak promoters may not be able to tolerate mutations that result in reduced activity, since even minor decreases in promoter activity could result in deleteriously low transcriptional rates and expression levels of these genes.

Furthermore, within individual genomes, less highly conserved sites may point to regions that can tolerate mutations without affecting the fitness of the individual, whereas mutations at more highly conserved sites may be lethal.

The method is based on the idea that recognition sites may correspond to localized regions with low-intensity energetic couplings with the rest of the protein, which allows them to undergo conformational changes, to be recognized by a binding partner, and to tolerate mutations with minimal energetic expense.

Furthermore, some genes tolerate a large spectrum of individual missense mutations throughout the protein sequence, while other genes do not (i.e., highly evolutionarily conserved genes presumably do not tolerate mutations well).

Rather, like other 'hard' divalent cations, barium does not tolerate mutations at the calcium-binding sites identified in our study.

We have investigated the ability of RSV to tolerate mutations in and around the U5 IR stem and loop.

This interpretation is somewhat analogous to the concept of genetic "buffering," in which populations may tolerate otherwise deleterious mutations in genes in order to maintain higher genetic diversity and thereby expedite the rate of adaption [ 43].