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Although the antagonistic effect of SU HW) appears relatively modest at individual loci, the large numbers of SU HW) sites in many LADs may together modulate chromosome organization to a significant degree.
The multiple functions of the unique retrograde motor myosin VI appear to be regulated in a number of ways; for example by the presence or absence of inserts in both the tail and motor domains, by PIP2/liposome binding, by phosphorylation, by calcium binding, by binding partners and possibly by other signals and modifications, which may together modulate its functions in the cell.
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Depending on this probability, the ACC then recruits the DLPFC and both structures may act together, modulating activity in other structures according to the task demands (see also Johnston et al. 2007).
SNP 285 and SNP309 thus may influence each other and together modulate the levels of MDM2 produced.
These molecules together modulate the axon growth from the retina to optic chiasm.
Our data suggest for the first time that a SNP in PARP2, rs878156, may together with other genetic variants modulate cancer specific survival in breast cancer patients depending on chemotherapy.
It is tempting to speculate that NleL, NleG and Tir may work together to modulate the actin pedestal formation.
Furthermore, kinases and phosphatases may work together to modulate the strength of a signal [ 49].
TRP-1 and TRP-2 are transmembrane proteins spanning melanosomal membranes and may act together to modulate TYR activity.
Taken together, spiny mice may modulate or (partially) switch the distribution of eumelanin and pheomelanin in the hairs.
Therefore, nobiletin and tangeretin, together with other bioactive flavonoids, may collectively modulate platelet function in order to reduce potential thrombosis risk.
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