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These results suggest that the surface compartments formed by the ECM hinder lateral diffusion of AMPA receptors and may therefore modulate short-term synaptic plasticity.
3-oxo-C12-HSL may therefore modulate NF-κB signaling via the direct interaction with PPARs.
Different second messengers may therefore modulate the odor response depending on stimulus length and strength.
Peroxisome proliferator-activated receptor (PPAR)α is a central transcriptional suppressor of inflammation, and may therefore modulate tumor growth.
This loop plasticity may therefore modulate the susceptibility of a given species to prion disease [32], [33], [34].
30 Mitochondrial dysfunction may therefore modulate HtrA2 activity at several levels.
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These immune suppressors may thus modulate HSC immunogenicity and, therefore, contribute to the "immune privilege" of HSCs.
Environmental factors such as visual cues may therefore potentially modulate the chance of hallucinations.
The cellular concentration of drugs within the heart may therefore be modulated by the intrinsic activity of CYP450 isozymes found in cardiac tissues.
The T-cell-inhibitory effect of IL-10 may therefore be modulated complicatedly upon exposure to an inflammatory environment in RA joints, where many cytokines are present substantially [ 10].
However, Ca2+ release from the lysosomes have been proposed to be amplified by Ca2+ release from the ER by a process of Ca2+-induced Ca2+ release, and may therefore also modulate proximal steps in the autophagy pathway., Moreover, recent work of different groups highlighted the possibility of complex, bi-directional functional interactions between lysosomal and ER Ca2+.
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