Sentence examples for may therefore mediate from inspiring English sources

To analyse which BH3-only proteins are induced in the absence of cytokine-mediated survival signals and may therefore mediate HSPC apoptosis, we isolated LSK cells from BM of wt mice and cultured them in the presence or absence of the cytokines TPO, Flt3L and SCF.

It should be noted that fish also appear to choose mating partners based on MHC haplotype, presumably via an olfactory-mediated process [ 53]; the OlfC receptors may therefore mediate chemoreception of peptide cues via such allosteric interactions, distinct from "orthosteric" ligand binding interactions within the conventional clamshell binding pocket.

However, GluMIs and type 2 OFF bipolar cells possess functionally distinct light-driven responses and may therefore mediate separate components of the excitatory synaptic input to AOFF-S RGCs.

These factors may therefore mediate critical developmental processes including the coupling of neurogenesis and gliogenesis and neuronal-glial interactions that underlie synaptic and neural network plasticity and homeostasis in health and in specific neurological disease states.

Creb1 may therefore mediate differentiation throughout the entire conducting airway epithelium though this needs to shown for other epithelial populations such as goblet and basal cells, which appear in the upper bronchial and tracheal epithelium.

RAS may therefore mediate autophagy addiction in combination with other factors.

The beneficial effects of exanatide on cardiac function and survival may therefore be mediated through drug-induced changes in the heart, the body, or both.

The relationship between eating psychopathology and SF may therefore be mediated through menstrual dysfunction.

The activity of Ha-AP10, a cationic and hydrophobic peptide, may therefore be mediated by its electrostatic interaction with anionic membrane phospholipids [ 23].

Previously reported associations between birth order and suicidality [ 13, 14] may therefore be mediated by sexual orientation, with birth order being merely a risk indicator.

Acclimatisation may therefore be mediated in part by alterations in oxygen delivery, but also by reductions in cellular oxygen demand, perhaps through hibernation/stunning or preconditioning pathways, or through improvements in efficiency of use of metabolic substrates.