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Gain of function mutations at these candidate loci may therefore confer enhanced MFC power generating properties.

Given the increase in MDR1 expression, we hypothesized that Apc mutation may therefore confer chemotherapeutic resistance.

'Inappropriate' formation, and aggregation, of DPR may therefore confer neurotoxicity and influence clinical phenotype.

The aphA1-IAB gene present on pJA144188 may therefore confer resistance to a selected set of aminoglycoside antibiotics in C. resistens DSM 45100.

Thus, the MTHFR 677C>T TT genotype may therefore confer both an increased as well as decreased risk of cancer [10,11].

Variants of the ABCB1 gene were associated with renal function in both Africans and Caucasians and may therefore confer susceptibility to nephropathy in humans.

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Such work has suggested that specific types of network wiring may increase network robustness and therefore confer a selective advantage.

It is likely that the knock down of Abi1 may impair these signaling pathways and therefore confer p185wt Abi1 shRNA cell disadvantage in an in vivo environment where the cells are exposed to numerous factors including cytokines, growth factors and extracellular matrix.

Increased risk for atherosclerosis may therefore be conferred by diabetes-associated biochemical processes that produce modifications in arterial PG.

This final check may firstly give a result earlier than mortality and therefore confer greater statistical power, and secondly be used as a check on the mortality result.

Our results suggest that well differentiated tumours may be associated with a more aggressive immune reaction and, therefore, confer a more favourable prognosis.

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