Indeed, pulmonary contusion may alter surfactant and thereby predispose to atelectasis [ 19].
Concomitant chemotherapy and corticosteroid treatment, in particular, may result in immunosuppression and thereby predispose to ongoing local sepsis after minor trauma.
This may lead to peripheral vascular resistance and thereby predispose a person to the development of hypertension and cardiovascular disease [ 150].
In this regard, it will also be interesting in future studies to look for genetic polymorphisms that may alter reactive astrocyte functions in certain individuals and thereby predispose them to certain disease processes.
Infection with KoRV possibly causes neoplastic disease [ 24], and may also compromise the immune system, thereby predisposing to other diseases including chlamydiosis [ 25].
First, weight gain and all associated metabolic disorders may predispose women to diabetes or heart disease, thereby predisposing them to morbidity and mortality [ 6].
It also conceivable that, in the presence of ongoing renal disease and inflammation, there may be disruption in the normal counter-regulatory mechanisms thereby predisposing such patients to AIN.
Inappropriate nutritional status or exposure to environmental chemicals and the accompanied alteration in growth and endocrine homeostasis may permanently change the fetus's structure, physiology, and metabolism, thereby predisposing it to various diseases in later life including mammary cancer.
Intrauterine xenoestrogen exposures may increase the number and/or size of adipocytes in early life, thereby predisposing individuals to obesity later in life, particularly if they consume a high-fat diet (Grün and Blumberg 2006).
Adverse perinatal environments influence fetal growth and may result in developmental adaptations that permanently change the physiology and metabolism of the offspring thereby predisposing individuals to metabolic, endocrine, and cardiovascular events [ 2].
