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The CD24hiCD148+ phenotype of B10 cells and B10PRO cells may thereby indicate their selection into the memory B cell pool during development, or they may represent a distinct B cell subset that shares common cell surface markers with memory B cells.
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The results thereby indicate that reablement may reduce the need for ongoing home-care, as well as for other health care services.
Our data thereby indicate that prion-like spreading of Tau-pathology may contribute to progression of disease symptoms in Tauopathies by affecting intrinsic functional critical networks.
Induction of PGIP under drought stress in the present study thereby indicate that PGIP is involved in multiple biological processes and may provide a link between drought stress mediated signaling and plant defense response.
Our results thereby indicate that COTC-related adverse events are an under-appreciated public health issue that may require greater scrutiny and improved surveillance.
This excluded the possibility that MALAT1 may regulate the function of SFPQ and PTBP2 by changing their mRNA or protein expression, thereby indicating other mechanisms may be involved.
In addition, our study shows that FHH3 can be associated with de novo AP2S1 mutations, consistent with a previous report (12), thereby indicating that patients may not have a family history of the disorder and that AP2S1 mutations may be associated with non-familial forms of hypercalcaemia and hypocalciuria.
As recently demonstrated, the bone marrow microenvironment has a lower oxygen concentration than other tissues, and stem cells are localized within the hypoxic regions [20], thereby indicating that hypoxia may be crucial for the maintenance of stem cells.
Importantly, these sublethal phenotypes were observed in many different organs and tissue types, thereby indicating that atrazine may be perturbing general mechanisms of tissue modeling during the stages we tested.
Merianda and co-workers have demonstrated that LFG localization in axons is sufficient to support axonal growth in dorsal root ganglionar cells, thereby indicating that LFG may have DR antagonist-independent functions.
In L. hokkaidonensis, GshF shared high similarity with that in L. coryniformis, which was a predominant isolate when we screened for psychrotolerant LAB in Timothy grass silage (see Additional file 1: Figure S1), thereby indicating that glutathione may facilitate psychrotolerance in both species.
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