Hence, enhanced activity in contralesional M1 might exert a negative influence on the motor network controlling the paretic hand and may thereby even impair recovery of function.
However, the use of initiators or crosslinkers during the hydrogel formation may cause cytotoxicity and thereby impair the biocompatibility.
An increase in maternal cortisol during late gestation may accelerate foetal gut maturation and thereby impair the acquisition of colostral immunoglobulins after birth [ 40].
Of all healthcare, there is a risk that the provision of maternity care, in particular, is structured in a manner that may undermine effective team behaviour and thereby impair outcomes.
These results indicated that CBHA may inhibit TNF- α-induced ATF2 and c-Jun nuclear activation and thereby impair AP-1 transcriptional activity and PAI-1 gene expression.
In conclusion, the present study demonstrated that inhibition of HDAC activity with CBHA may increase MKP-5/MKP-1 expression, abrogate TNF- α-activated MAPK/AP-1 signaling and thereby impair PAI-1 expression in human PMCs.
Similarly, fibrillar tau tangles may increase the diffusion-limiting effects of the microtubule network, with which the protein physiologically interacts, and thereby impair active transport along microtubules.
Inappropriate or excessive regret can thereby impair future decision-making.
Although these oxidized components are quickly repaired or eliminated, oxidation may alter their functional effects, thereby impairing various cellular processes.
In addition to the 5 initial paired maternal and cord blood samples, we examined an additional 13 paired maternal samples infected with malaria (5 intervillous and 8 peripheral venous blood) at delivery, to assess whether MSP1 may be complexed to antibody, thereby impairing its detection.
