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These transcription factors may then regulate Fe-deficiency-responsive genes lacking IDEs and CACGTGG in their promoter regions [44].
A crosstalk between adipocytes and other cells in the IFP may then regulate the cellular functions both in the cartilage and the synovium and promote articular changes associated with OA.
With the extended protein longevity, lncRNAs may then regulate protein occupancy on chromatin during cellular maintenance, as well as aid in transmission of epigenetic regulators across cell generations.
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The released gastric leptin [10] enters the lumen of the intestine [12], [30], where it may then up-regulate GLUT2/GLUT5 transporter activity to match dietary intake.
As the potentiation of synaptic strength increases the local dendritic excitability and subsequent Ca2+ influx [18], the expression level of IA in dendrites and synaptic sites may then be regulated by neurons to initiate secondary computational processing throughout the neuron.
The fine-tuning of replication timing during S phase may then be regulated by small additional local variations in the H1 phosphorylation pattern, in line with recent observations [ 20].
Future work is needed to validate this RNA transport hypothesis and to identify specific RNA molecules that can be bound by CNP and whose transport and translation may then be regulated.
"John Kerry's approach to the Second Amendment has been to regulate, regulate and then regulate some more," Mr. Cheney said.
"But if you're going to regulate drones, then regulate binoculars," he said.
Increased CXCL12 may then down-regulate CXCR4 [ 36].
In turn, Rab32 and Rab38 may then feed back to regulate yet further Rabs, since the VARP exchange factor for Rab21 is a Rab32/38-binding Rab32/38-binding
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