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It has been speculated that LEDGF/p75 may tether PICs at specific sites by interacting through its PWWP domain with specific histone modifications associated with transcriptional elongation.

This region may tether ribosomal 40S subunits to the mRNA following termination and a short region of the TURBS, motif 1, with complementarity to helix 26 of 18S rRNA has been implicated in this process.

Thus, PSD-95 may tether two protein complexes, stargazin/AMPAR and ADAM22/LGI1.

CALM/AF10 may tether its interaction partners into these endocytic vesicles and thereby disturb their physiological function.

We also found that the RA-domain of PI3Kγ has no effect on channel activity, suggesting that PI3Kγ may tether to CNGA1 for its activation.

The robust synaptonemal complex (SC) assembly in spo-11 rec-8 worms suggested that SC proteins may tether sister chromatids independently of cohesin.

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Similar(51)

Considering the role of SNARE proteins both in cell division and in intracellular vesicle-mediated transport events and membrane fusion, - we had anticipated that SNARE disruption may lead to virion tethering to the plasma membrane or virion-virion tethering, defects similar to those caused by Tsg101 depletion.

The presence of fibrosis renders reoperations risky, and in some patients fibrosis may lead to nerve root tethering.

This slows down the spider's movement and may help tether the spider to the relative safety of a floating object.

Though the usual obstacles to enterprise may temporarily tether him, it is safe to assume that at least one concern that crosses the mind of all canny would-be entrepreneurs -- is this an impossibly hokey idea?

Here they reveal the full complement of SNARE proteins needed and report that a domain of TANGO1 may help tether ERGIC membranes to the ER as part of the present process.

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