Sentence examples for may target either from inspiring English sources

Exact(7)

Since the initial results indicated that EA may target either β-catenin itself or its downstream factors, we next explored whether the drug could directly interact with any component of the β-catenin complex.

Experiments with the cell-based reporter system demonstrated that EA inhibited Wnt/β-catenin signaling mediated not only by Wnt3a, but also by Wnt/LRP6, Dvl and β-catenin, respectively, suggesting that the drug may target either β-catenin itself or its downstream factors.

In this regard, chemical-induced carcinogenesis model serves vital roles in identification of novel chemopreventive agents which may target either one or plausibly multiple signaling pathways.

While the regulation of longevity requires functional DAF-2/DAF-16 signalling, the control of oxidative stress resistance involves a DAF-2 independent, DAF-16-dependent pathway, suggesting that Klotho may target either DAF-2 or DAF-16, depending of environmental conditions.

While lifespan regulation requires a functional Daf-2/insulin/Igf-like signalling cascade, the control of oxidative stress resistance involves both a DAF-2 independent and a DAF-16-dependent pathway, suggesting that Klotho may target either DAF-2 or DAF-16, depending on environmental cues.

46, 47, 50 Depending on the technology used, tests may target either the 18S gene directly or its associated mRNA.

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Similar(53)

Conversely, miRNAs that are distinctly upregulated in either oligodendrocytes or Schwann cells may target proteins and/or control processes that are specific to either PNS or CNS myelination.

Thus, the observed interactions between Mcm2-7 and the various regulatory factors may target key enzymatic activities, either DNA unwinding or regulation of the Mcm2/5 gate.

Our in silico analysis suggests that miRNA may target preferentially duplicated R-genes either deriving from WGDs and more interestingly from local tandem duplications (i.e. clusters).

Owing to the cross-talk between NF κB and ROS MAPK pathways, singly targeting either pathway may not be sufficient for inducing cancer cell killing.

Further studies investigating these molecules may lead to molecular tests that can aid in the identification of patients who are likely to respond to specific antipsychotic treatments and who may benefit from adjunct therapies targeting either inflammatory or metabolic pathways.

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