Exact(1)
SipA may support actin assembly even though the free G-actin content is below the critical concentration that is physiologically necessary for actin polymerization.
Similar(59)
Actin polymerization may support membrane invagination and scission during endocytosis.
Our findings may support a role of integrin-mediated actin regulation in VPA teratogenicity, even though we were unable to observe any apparent reorganization of the actin cytoskeleton, as visualized by phalloidin staining (data not shown), in P19 cells treated with VPA at the present concentration (1 mM).
The observation that overexpression of PARP in D. melanogaster disrupts the organization of cytoskeletal F-actin resulting in aberrant cell and tissue morphology [65] may support this connection.
This may support the theory.
Therefore, the chromosome segregation defects identified in this study may also reflect a requirement for the eggshell in supporting actin-dependent chromosome capture.
Thus the process of microvilli formation and shaping in a period immediately after eclosion, before cuticle solidifies, may be supported by actin filaments.
Moreover, the expressed I-BAR domain forms a submembranous coat that may structurally support these transient actin-free protrusions until they are further stabilized by the actin cytoskeleton.
Instead, our data support that actin filaments may be involved in the virion assembly and budding process of the coronavirus replication cycles.
Some may secretly support the invasion.
The N-terminus of the Tir domain binds several host focal adhesion proteins, including α-actinin, talin and vinculin, and cortactin to which may promote actin networks that support the pedestal [17], [18].
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