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Its over-expression in resistant mosquitoes may suggest modulation of salivary gland cells due to the presence of the acetylcholinesterase resistance gene.
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As it may be inferred that progesterone production in lactating postpartum women is predominantly of adrenal origin (Wirth et al. 2007), this finding may suggest that modulation of startle during affective anticipation is dependent on HPA axis reactivity, although cortisol has previously been associated with elevations only in baseline startle (Buchanan et al. 2001).
This inconclusive data may suggest that the modulation of cancer risk depends not only on a single gene/SNP, but also on a joint effect of multiple polymorphisms (or haplotypes) within different genes or pathways, in close interaction with environmental factors.
This attenuation of the HR response was also observed with propranolol, which may suggest increased parasympathetic modulation of the orthostatic response during psychological stress.
Furthermore, while the significant difference detected between healthy donors and lung cancer patients with no history of chemotherapy treatment (P=0.01) may suggest chemotherapy-mediated modulation of NKT cell numbers; the low subject numbers (n=4) in this subgroup does not facilitate accurate analysis.
Therefore, our observations may suggest tissue-type specific modulation of inflammation-related processes.
These differences in ER modulation may suggest different mechanisms of action between the two related SERMs and may portend different long-term outcomes.
This may suggest that nAChR-mediated modulation of thalamic inputs to the PFC is specifically targeting layer V pyramidal neurons, which projectmainly to the striatum and hypothalamus (Gabbott et al. 2005).
In this context, the activity of the essential oil of F. vulgare (100 and 200 mg/kg) in relieving anxiety in this model may suggest a possible positive modulation of the GABA-A/benzodiazepine receptor complex.
The finding that application of METH after pre-application of SCH23390 did not increase in baseline synaptic transmission further may suggest that the METH-mediated modulation of fEPSPs might in part be due to the release of endogenous dopamine and subsequent activation of D1/D5-like receptors (also see figure S1).
This finding may suggest that GATA-4 plays a role in modulation of the thin filament.
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