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The positive correlation between ABCA8 and p25α may substantiate a link between ABCA8 and pre-GCIs disease events in line with the findings of Song and colleagues [ 28] outlined above.
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Clinical records are often not available to testing labs, though in some cases they may substantiate or cast doubt on a variant's pathogenicity.
Since oxidative stress is implicated in the pathophysiology of dementia, the findings of this study may substantiate the value of scopolamine-induced amnesia in rats as a valid animal model to screen for drugs with potential therapeutic benefit in dementia.
While the data with the trans-wells were unambiguous, cell-cell contact may substantiate the anti-HIV effects.
Although transcriptomics data indicate potential changes in enzymatic pathways, only direct data on metabolite levels may substantiate these findings.
Therefore, cytochalasins have unique microfilament-directed mechanisms that may substantiate potent drug synergy with agents that target microtubules or nucleic acids.
We hypothesize that the occurrence of distinct patterns of molecular evolution in each clade of orchid DEF-like genes may substantiate the hypothesis that each of them is associated to distinct protein- or DNA-binding capabilities.
Inspection of data presented in Table 1 and in Figures 1 and 3 may substantiate the idea that the PA signal is lower in the case of more coarse flours.
Expectations are that, with the decreasing costs of genomic and proteomic applications, the investigation of large population-based data sets will provide the opportunity to identify more homogeneous disease subtypes and investigate biomarkers, so that biomarker studies may substantiate disease sub-groups.
If sensitive and reproducible, changes in biomarker levels during treatment may thus help to substantiate a genuine effect on specific biological processes in PoC trials.
Note, however, that PRO instruments that measure a simple concept may not be adequate to substantiate a more complex claim.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com