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Studies with other non-cereal monocots have found that some, but not all, introns derived from cereal monocots may stimulate gene expression, and dicot-derived introns result in relatively lower levels of IME.
Previous studies have indicated that hypoxia may stimulate gene expression through different pathways, including ERK, JNK, p38 MAPK and PI3K/Akt [ 30], and therefore hypoxia may increase the expression of myocardin through one of these pathways.
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Transcriptional activators may stimulate gene-specific expression by recruiting the co-regulator complexes Mediator, SAGA and/or Swi/Snf as well as RNA polymerase II to promoters.
These findings suggest that elevated CREB expression may stimulate genes involved in the lipid biosynthesis pathway such as SCD [ 51] and HMG-Co synthase [ 53], resulting in an increase in IMF content within muscles.
Isotretinoin and all-trans retinoic acid may stimulate FoxO gene expression.
Alternatively, the presence of heterologous Etn element sequences in T Wis transcripts may stimulate posttranscriptional gene silencing by an RNA-induced silencing complex (RISC -based RISC -basedation pathway which could taRNAi degradation of wild typathwayscripts [ 14].
He thinks that these molecules may get into the blood and stimulate gene activity that leads to the closure of the barrier.
These predictions suggest that ABA or ethylene alone stimulate gene expression which may be required for ROS-induced maintenance of stomatal closure.
In this case, further depression of HDAC activity by HDACi might inhibit transcription factors required for inflammatory gene production, and instead may stimulate transcription of genes involved in cell cycle arrest and apoptosis.
In their review paper, Horan and colleagues propose that the trauma, stress and fear associated with CSA may stimulate enhanced CRH gene expression and chronic overproduction of CRH in the brain, making a woman susceptible to elevated placental CRH gene expression during pregnancy and consequently, increased risk of PTB [ 51].
This observation is consistent with the idea that p68 has little effect on ERα function physiologically, but that the elevated p68 levels found in tumours may stimulate ERα-mediated gene expression in a pathological context.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com