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It has also been shown that CD163-expressing cells possess pro-angiogenic activity and may stimulate formation of new blood vessels through activation of proliferation of endothelial cells [ 41].
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Similarities in VASP adhesion formation during periodic protrusion and retraction in both periodic blebbing and periodic contractions of the lamellipodium further suggested a common function of adhesion formation between these two motility modules, and the transient force generation observed in both modules (see previous section) may stimulate the formation of such adhesions [47].
Previous also showed that lowering the pH value to 2.5 would result in high monacolin K and citrinin concentrations as well as high biomass in fixed dioscorea amount, implying that pH value may stimulate the formation of monacolin K and citrinin through increasing Monascus cell amount (Lee et al. 2007).
Hence, persistence of these apoptotic bodies may stimulate granuloma formation.
This supported the evidence that hyperglycemia condition may stimulate the formation of autoantibody against AGE.
The latter indicates that a combination of readily available saccharides, vitamins, and macronutrients in a pH neutral environment may stimulate toxin formation.
As bone formation occurs preferentially in areas in which the strains are higher [ 9], we hypothesize that both PS and ES may stimulate local bone formation.
These results are consistent with the notion that BDNF may stimulate both the formation and turnover of nascent adhesions, since stabile adhesions persisting for longer than 15 min would be expected to recruit α-actinin.
Thus, an orexin-mediated increase in the release of GABA and glutamate during early development might enhance excitatory postsynaptic activity indirectly through these two classical neurotransmitters (van den Pol et al. 2001) and thereby orexin-A and orexin-B may stimulate the network formation and cell-to-cell interactions.
The increase in β-cell mass induced by geniposide raised the possibility that this compound may stimulate new β-cell formation.
Consequently, an enhanced understanding of the pathogenic signaling mechanisms involved in TAA formation may stimulate the development of more efficacious, safe, or targeted therapeutic options to prevent or treat this deadly complication of MFS.
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