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In this regard, it is possible that early Brn-3b increases in injured cardiomyocytes may stimulate distinct targets, including cell cycle genes, involved in initial responses to injury.
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Primarily, the stimulation of P2X receptors causes Ca2+ influx and can stimulate distinct Ca2+-dependent signalling cascades, which may have particular propensity to elicit cell death [13] e.g., by ischemia-induced excitotoxic glutamate release [14], or the activation of extracellular signal-regulated protein kinase (ERK) by P2X2 receptors [15].
The different stimuli were chosen to activate distinct cellular receptors (T cell receptor, Toll-like receptors) and stimulate distinct immune cells (lymphocytes and antigen-presenting cells).
As Timp1 may stimulate cell proliferation by using several distinct signalling pathways, such as MAPK, the inhibitory effect of CLA on this gene may reduce lymphoproliferation.
As a putative venom component, it may stimulate BK B2 receptors (B2Rs) in a distinct manner relative to the fragile mammalian agonist BK.
Furthermore, the enhanced AMKP activation may stimulate muscle glucose uptake, this occurs through a distinct mechanism than the insulin-signaling pathway [ 34].
Although BMP2 signaling component is distinct from the known Wnt/ β-catenin signal transduction pathway, they may stimulate processes that cooperate with activated β-catenin to promote osteoblast differentiation.
We can live without extremists, however much they may stimulate our faculties of lust and rage.
But studies have also suggested that estrogen, either natural or as a drug, may stimulate adenocarcinomas.
Such calculations may stimulate the experimental investigations.
The information provided by this survey may stimulate educational interventions.
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