Sentence examples for may stabilize inactive from inspiring English sources

These results support previous co-immunopreciptation and cross-linking studies suggesting that members of this quinazoline family of TKIs may stabilize inactive HER heterodimers while inhibiting phosphorylation and downstream signaling [ 46- 48].

These results are consistent with several studies showing that HER1 tyrosine kinase inhibitors may stabilize inactive HER1-containing dimers, most notably gefitinib binding to the open or active HER1 kinase conformation [ 46- 48].

Simard, J.R. et al. High-throughput screening to identify inhibitors which stabilize inactive kinase conformations in p38α.

Macrolides may stabilize lung function in patients with established BOS.

At some point, env diversity may stabilize or even decrease.

AvrA may stabilize TJ structure by dampening the inflammatory response.

Nonmalignant stenoses may stabilize over time as the tissue stiffens.

Alternatively, CXCL10 and CXCL11 may stabilize distinct receptor conformations.

We hypothesized that active transcription may stabilize the holocomplex.

This suggests that interaction with activated Gαq may stabilize Fhit.

In contrast, binding of Type II inhibitor 2 to the inactive conformation helps to stabilize the inactive conformation of the protein.