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As DGR RTs only have relaxed fidelity at As, changes in the binding pocket may specifically modify the interaction with adenine residues.
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Alternatively, the nucleosomes flanking the disassembled region may be specifically modified and signal that the intervening region should remain disassembled.
The design of specific inhibitory molecules, called miRNA sponges, may allow the inhibition of several miRNAs simultaneously, with a very high efficacy and the ability to specifically modify the dynamics of any pathway [ 108, 109].
Therefore, it is possible that the nature of the epigenetic mark that specifies a nucleosome-depleted PHO5 promoter may be a specifically modified histone that remains in the -1 to -4 nucleosome positions.
Screening in 19Q nematodes suggested that greater than 90% of these genes specifically modify 128Q cytotoxicity.
First, DNA or chromatin, or even certain DNA sequence elements or specifically modified chromatin, may increase the affinity of AIRE for DNA-PK.
All of the numerical investigations were carried out by specifically modifying the control stope.
It is in fact a nanofiber whose surface chemistry can be site- specifically modified [1].
The properties of optical minigastrin probes can be specifically modified by the introduction of spacer sequences.
This year also saw the introduction of aeroplanes specifically modified for aerial combat.
This effect was specifically modified by CSKN1A1 expression.
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