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These findings raise the possibility that miR-29b may specifically interact with hPGRN 3'UTR.
Taking into account the extensive profile of CT activity, along with the successful leakage experiments on anionic model membranes lacking sulfatides [6], [19], [20], it is reasonable to propose that CTs may specifically interact with other anionic membrane compounds as well.
Ultimately, this could help in identifying other RA genetic factors that may specifically interact with only one of the HLA-DRB1 genotypes.
However, RACK1 localization follows the localization pattern of iMELK suggesting that in the epithelial cells it may specifically interact with iMELK at the tight junctions.
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This includes inactivation of proteins on the slide surface, mis-folding or RNA cross-hybridization in solution, and finally, many annotated RBPs act in protein complexes (e.g. ribosomal proteins) and thus may not specifically interact with RNAs on their own.
In addition, the inhibitor-targeted dTAF2 IDRs are rich in lysine residues that may non-specifically interact with negatively charged DNA backbone.
Improved understanding of how Rho family GTPases and their downstream effectors mutually and specifically interact in human cancers may throw more light on the best therapeutic approach to cancer and might lead to new treatment protocols.
In addition, they specifically interact with σ54 RNA polymerase [1].
Thus oxidized Nm23-H1 seems to specifically interact with TrxR1 in vivo.
As expected, HuR was found to specifically interact with the 3'terminal region of the EphA2 3'UTR.
Taken together, these results show that the cytoplasmic tail of ErbB4 can specifically interact with nucleolin.
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