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Therefore, hypoxic ischemic injuries may specifically induce neuronal death in these areas.
Next, we tested whether Jurkat-TRAIL cells may specifically induce apoptosis via the death receptor pathway in vivo.
In contrast, starvation may specifically induce stress in cancer cells because cancer cells struggle to adapt to the loss of external growth factors by adjusting autonomous growth stimulation and reprogramming their metabolism thereby maintaining continuous proliferation [ 13].
The stimulation of luciferase activity by clodronate and E2 were both completely abrogated by simultaneous incubation with 4-OH-TAM or fulvestrant, again suggesting that Clod may specifically induce ER activation.
As an example, the higher incidence of MSI/LO Hin alleles of Tp53-Alu (chromosome 17) may specifically induce the initiation of these consequences, which might be reasonable for the multi-task protein TP53, which plays a role in activating MMR in response to DNA damage [ 52].
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One possibility is that these pathways may be specifically induced by P. falciparum co-culture with orthochromatic cells to provide nutrient or metabolic factors.
To identify genes that may be specifically induced during viral clearance in chimpanzee X0190, the database of expression levels was queried for genes above the confidence interval at 13 weeks post-infection (>2.2-fold induction) and below this interval at 4, 6 and 40 weeks (<1.9-, 2.1-, and 2.4-fold induction).
This implies that apoptosis may be specifically induced in inflammatory endothelial cells.
In particular, northern blot analysis suggested that our strategy allowed us to identify some genes that may be specifically induced at high levels in Cx whereas are not expressed or expressed at very low levels in Ox.
In fact, some other epitopes which induce activation of CD4+ T cells but not CD8+ T cells from hTERT have been identified [41], [42], suggesting that some epitopes that specifically induce other immune cells may also exist.
The summation of these studies indicates that the identification of compounds which can specifically induce and/or activate ERα/β heterodimers or ERβ homodimers may have therapeutic potential.
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