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It is therefore theoretically possible that EPA may so alter sarcoplasmic reticulum (SR) function that it blocks cytosolic calcium increases and calpain activation following endotoxin administration.
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Cytokines are involved in the inflammatory response, so altering their release may reduce inflammation.
Emerging evidence suggests OPCs may be crucial for mediating inflammation51 and may entrap dystrophic axon tips within the glial scar52, so altering OPC numbers would confound an interpretation of the role of oligodendrocyte remyelination in locomotor recovery.
Abnormal DNA methylation may affect DNA-protein interactions and so may alter all processes in which such interactions occur.
Failing to do so may alter testing results, leading to misdiagnosis and inappropriate treatment.
Furthermore, HCMV is a pathogen of the gastrointestinal tract of HIV/AIDS patients and so may alter nutrient absorption, and can invade the central nervous system, possibly affecting development [ 3, 4, 27, 28].
For XD4, the inversion event leaves GCN4 without its standard 3′UTR sequence and so also may alter its expression or regulation.
RTMark offers ideas for anti-corporate pranks without charge on the Web, much as online groups in the open-source movement believe in making technology available to users so they may alter it as they see fit.
Different stages of apoptosis may differentially alter autoantigens, so that early compared with late apoptosis results in different autoantigen fragments [ 43, 50].
The plan Coach Byron Scott laid out during Mutombo's recovery, to bring him back to the starting lineup slowly, may be altered so that Mutombo is playing even less.
The text on navigation buttons may be altered so that the user can easily navigate and interact with the interface and understand the messages being displayed.
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