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Outbreaks can lead to significant increase in the need for ICU beds, but may simultaneously reduce the available beds.
Although they are associated with higher treatment costs, COX-2 inhibitors may simultaneously reduce costs associated with adverse events, hence, their overall economic benefit should be assessed.
The unique roles of IRF-1 in the enhancement of HIV-1 replication and induction of death ligand TRAIL provide a potentially novel therapeutic target, and inhibition of IRF-1 may simultaneously reduce HIV-1 viral load and alleviate macrophage-mediated HIV-1 pathogenesis.
The range of other pharmacologic options to treat osteoporosis has been rapidly expanding, several of which (e.g. raloxifene [ 20, 53]) may simultaneously reduce the risk of breast cancer.
Some interventions may simultaneously reduce the probability of HIV transmission per risk event and also prolong life expectancy, and, therefore, the duration of time over which HIV can be transmitted.
Similar(55)
In this instance, strategies that combine target-directed therapies with non-targeted/ablative therapies may help to simultaneously reduce tumour burden, plasticity and complexity.
Alternatively, microgeographic, seasonal and female quality constraints may be simultaneously reduced if one can analyze the changes of mate attractiveness within individual females (see [58]), e.g. in random regression animal models [84], but this requires very large datasets.
The deamination-independence of the restriction mechanism suggests that a catalytically inert APOBEC3G protein, such as E259Q, may be equally potent and simultaneously reduce the risk of cancer-promoting mutagenesis.
Inhibition of IFN- γ signaling may thus represent a novel strategy to simultaneously reduce inflammation and bone loss in common forms of osteoporosis [ 22].
In addition, exclusion of parakeets would simultaneously reduce the foraging benefits of urban areas for the parakeets, which may in turn limit the persistence of the parakeet populations.
"But we must simultaneously reduce the hassle factor.
Related(20)
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