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Based on our study, we presume that besides susceptibility to PC, males from different ethnic and geographical regions may show sequence and copy number variations in the DYZ1 arrays.
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Genes may show larger sequence diversity between "alleles" within individuals than between the same sequences in different species (Table 1).
This finding suggests that if HOTAIR has orthologues in mammals and other vertebrates, they may show low sequence conservation.
The number of Mhc genes can differ greatly between and within species, and may show no sequence orthology between genera or orders – e.g. class I gene number and organization differences between human and chimpanzees (reviewed in [ 10]).
The shorter sequences may lack a characterized protein domain or may be too short to show sequence matches, resulting in false-negative results.
While, 55.95% genes less than 300 nt long, could not be matched to known genes, suggesting that the shorter sequences may lack a characterized protein domain or may be too short to show sequence matches, resulting in false-negative results.
Since the shorter sequences may lack a characterized protein domain or may be too short to show sequence matches, resulting in false-negative results, the contigs which were less than 200 bp in length were excluded in our homology searches (see Table 1).
The shorter sequences may lack a characterized protein domain, or they may contain a known protein domain but not show sequence matches due to the short query sequence, resulting in false-negative results.
Proteins that have homology may show strings of sequence with perfect alignment, interspersed by breaks or openings where the sequences are not similar or missing.
Thus, the high substitution rate of these non-coding regions may show effects of sequence saturation.
For example, a comparison of sequences may show changes in the repeat sequence that formed a promoter for the putative RNA gene locus in S. typhi.
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CEO of Professional Science Editing for Scientists @ prosciediting.com