Overall these alterations may serve to facilitate the potential survival of gonadal tissue in the males.
It would be of great interest to investigate if these alterations may serve as biomarkers for the prediction and/or treatment of endometriosis.
These altercations may serve as distractions from the country's economic woes, but they provoke much bitterness.
The detection of a ret/PTC-1 rearrangement in Case 7 (Hürthle cell variant of papillary carcinoma) suggests that GRIM-19 mutation may serve as a predisposing alteration for the occurrence of tumours with cell oxyphilia.
Cancer Genome Atlas Research Network (2012) recently sequenced 178 human SCCs, identifying numerous genetic alterations that may serve as valuable therapeutic targets.
Blood based biomarkers that may serve as surrogates for tumor alterations and hereby avoid invasive diagnostic techniques are always preferred.
Analyses of the patterns of epigenetic alteration are providing important insights into the origin of this disease and have identified specific alterations that may serve as useful diagnostic and prognostic biomarkers.
13 Therefore, PTEN may serve as a characteristic molecular alteration of MTOE into endometrioid carcinoma.
This compiled information may serve as a benchmark for the alteration of existing ligands to design novel potent molecules with lesser side effects.
Chromatin itself may serve as a target of age-related change; significant alterations in chromatin structure occur during senescence of mammalian cells in vitro, and perhaps in the context of the whole organism as well [ 5].
