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Increased expression of IFN-γR in CD25/IL-17 CD25/IL-17nsitize to the effects of IFN-γ that is secreteDKOy T cells and NK cells.
While this approach can not distinguish between the functions of individual AP-2 family members, it suggests that interfering with AP-2γ may sensitize to apoptosis even in the absence of functional AP-2α.
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Reduced levels of Bcl2 and Mcl1, as noted in FO B cells, may also sensitize to apoptosis, as both proteins are clearly critical for B-cell survival.
Beginning with this overview may also sensitize to look for particular things.
Thus, it is likely that other factors in lung cancer cells may sensitize cells to gefitinib in addition to EGFR gene mutation and the amplification detected by FISH.
We speculate that oxidation of the lysosomal Ca2+ channel during reperfusion may sensitize it to NAADP, in a manner similar to the redox regulation of RyR2.
It is fundamental to assess whether a preexisting injury may sensitize lungs to the deleterious effects of mechanical ventilation.
Finally, the authors show some data suggesting that SPOP mutations may sensitize cells to PARP inhibitors, which have been shown to be synthetic lethal with BRCA1 mutations.
We reasoned that halving the gene dosage of endos may sensitize females to reduced dosage of other genes functioning with endos to control meiotic maturation and/or early embryonic mitoses, leading to reduced fertility of double heterozygous females.
Based on the current knowledge on the functional role of BAG3 in cardiomyocytes, it is reasonable to propose that the loss of BAG3 regulation may sensitize cardiomyocytes to stress conditions.
To determine if certain structural and physicochemical properties may sensitize sulfonyladenosines to efflux pump activity, we carried out PCA and Pearson analyses incorporating the normalized accumulation levels in the presence of efflux pump inhibitors.
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CEO of Professional Science Editing for Scientists @ prosciediting.com