Sentence examples for may sensitize cells from inspiring English sources

It is interesting that NSC11668 is itself an ABCG2 inhibitor [36], suggesting that it may sensitize cells to its own ScPma1p activity.

It is anticipated that chemotherapeutic agents may sensitize cells to CDK inhibition [35].

The delay of onset in cell death and the low rate of apoptotic cell death among cortical neurons lacking presenilins suggest that loss of presenilins may sensitize cells to die rather than immediately triggering apoptosis.

Inhibition of NF-κB activation may sensitize cells to CPT [ 41, 42].

This phenomenon remains currently unexplained but is in line with previously proposed cell cycle checkpoint functions of this protease, that when absent may sensitize cells to apoptosis.

Thus, it is likely that other factors in lung cancer cells may sensitize cells to gefitinib in addition to EGFR gene mutation and the amplification detected by FISH.

However, TNF-R1 is expressed in all studied cell lines and it was shown previously that TNF-R2 can induce apoptosis by strongly enhancing the activation of TNF-R1 by TNF-α and also by inhibiting nuclear factor kappa B-mediated protection (30), indicating that TNF-R2 overexpression may sensitizes cells to TNF-a-mediated apoptotic signal after γ-irradiation.

In addition to the potential of growth factor inhibitors to reverse pro-survival signal, they may also sensitize cells to irradiation by altering cell cycle control.

The tolerability of this combination provides an opportunity to consider a 3-drug regimen combining a second apoptotic stressor, which may further sensitize cells to HCQ without overlapping toxicities.

Under chronic inflammatory conditions, TNFα may, however, sensitize cells to FasL-induced apoptosis in an NF-kappaB-independent manner, as it has recently been suggested by Schmich et al. (2011) (see below).

In fact, a recent study suggested that apigenin may sensitize leukemia cells, prostate cancer cells, and colon cancer cells by inducing the expression of death receptor 5, which, in combination with exogenous tumor necrosis factor-related apoptosis-inducing ligand, acts synergistically to induce apoptosis while having no effect on normal cells [ 32].