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The early start of the ADVOS procedure (which was necessary due to the short lifetime of the animals and the expedited nature of events in the model) is indeed a disadvantage that may restrict extrapolation to critically ill patients.
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However, the limited number of workers in our study may restrict the feasibility of making a detailed adjustment to confounders on all person-related factors and thus limit the extrapolation of our findings to workers in other industrial settings.
Others may restrict individual freedom more severely.
They may restrict blood and air flow.
Although participants' perceptions of DE learning experiences may be illustrative and/or indicative of broader trends, qualitative epistemology restricts extrapolation of findings beyond the present sample and aims to examine emerging themes in-depth rather than be quantitatively representative of broader populations (Cohen, Manion, & Morrison, 2007; Neuman, 2011; Ragusa, 2012).
The workers were mostly in manufacturing, which may limit extrapolations to other industrial sectors.
That may needlessly restrict participation in a trial.
The limitations of our study include the following: (1) retrospective chart review, (2) convenience sample, which will restrict the extrapolation of prevalence data to general population, and (3) lack of data regarding the duration of HTN, which will be important as the vascular stiffness and nerve compression may worsen with prolonged hypertension.
Source: Apple may not restrict free iPhone apps [Electronista].
The limitations of the study are the small sample size and the specific selection of pGDM, which restrict the extrapolation of the results to all pGDM.
Parents may severely restrict your creativity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com