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The additional studies are also likely to involve more experiments in animals, and may require studies in non-rodent species.
Given that the calcium transients could not be detected in anesthetized mice, a full understanding of the mechanisms underlying associative learning may require studies of the conscious brain.
The competing risk issue between stillbirth and neonatal death is simply resolved by using perinatal death as an outcome, though there are socio-cultural reasons that may require studies to focus on stillbirths or neonatal deaths separately.
It is possible that chronic immunosuppression, as given to transplant recipients, could allow for some level of beta cell replication in the native pancreas, but addressing this question has proven difficult in recent clinical studies [ 24] and may require studies of the native pancreas if this can be recovered from immunosuppressed transplant recipients.
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Clarifying inconsistencies between studies, such as the finding of an OS predictive effect of EREG in K-ras mutant status patients (Pentheroudakis et al, 2013), which was not observed in our study, may require additional studies.
All this depends on the investigator's interpretation and may require further studies.
The French authority, the Haute Autorité de Santé, can request additional data, which may require new studies, during its assessment procedure.
However, interaction effects (effect modification) may require huge studies to confirm [28], much larger than even the very large consortia that have been put together in the genetics of type 2 diabetes.
Whether there is any link between these intermediate pathways may require further studies.
Thus, the role of ticks in the epidemiology of ASF in Nigeria may require further studies.
It may require further studies to determine which other factors are responsible for intraindividual changes in choroidal thickness.
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