Exact(6)
This may require sampling at submaximal spatial resolutions (largely, we used 64 × 64 pixels, even though the chip contains 128 × 128).
Ultimately, to derive detailed mechanistic insights from leachate compositions may require sampling and characterisation of tephra deposits on an equal or greater scale than that associated with MSH.
In other words, 93% of the geographic differences in gene expression were timepoint dependent, which strongly suggests that a comprehensive description of geographic differentiation in D. melanogaster transcript abundance may require sampling that accounts for circadian time.
On the other hand, sedentary species such as oysters and specific local habitats like tidal creeks may give a very accurate picture of localized effects of contaminants, toxins and pathogens, but gaining a picture of more widespread impacts may require sampling of sentinels in numerous locations.
Nevertheless, it should be noted that they were adult twin pairs; conclusive determination of 25(OH D relation to MS risk may require sampling many years before disease onset or even sampling of mothers during gestation.
Although imaging findings, particularly with CT and PET, can suggest the correct tumor stage, imaging is imperfect in this regard; enlarged and/or hypermetabolic lymph nodes may require sampling for confirmation of presumed tumor stage.
Similar(54)
Projects may require samples accrued on more than one trial.
In some cases this may require samples from subjects of different studies, and staff work with requestors to insure that the samples meet their research objectives.
The main weaknesses of PCR-based assays are that they do not preserve tissue morphology, may require sample macro- or microdissection to enrich for tumor content, heterogeneity can be missed and contamination with normal or ductal carcinoma in situ may lead to both false-negative and false-positive results.
For example, water monitoring using invertebrate diversity indices may only require samples be identified to family to be useful.
Note also that a cost-efficient inventory may require different sampling intensities in different ecozones.
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