Sentence examples for may require dosing from inspiring English sources
Patients taking ropinirole may require dosing adjustments with the introduction, withdrawal or dose adjustment in any of these medications.
Some patients in the 15-min cohort had the option of receiving 2- to 5-min infusions on day 8. Intravenously administered drugs are essentially 100% bioavailable; therefore, switching to an intravenous formulation from a <100% bioavailable oral formulation, such as carbamazepine, may require dosing adjustments to maintain therapeutic plasma drug concentrations.
But to obtain enough of these estrogens to counter a severe case of hot flashes or night sweats may require doses that are as strong, or nearly so, as pharmaceutical estrogen products and may present comparable risks.
This data indicates that the potential beneficial effects of statins in EAU may require doses greater than those used in the routine treatment of hyperlipidemia in humans.
Therefore, modulation of CYP3A enzyme activity in smokers may require dose adjustment for some inhaled drugs.
These factors should be taken into account when starting an antidepressant and in some cases may require dose adjustment.
As tolvaptan is also primarily metabolized by the CYP3A4 pathway, coadministration of calcium channel blockers, macrolide antibiotics, or azole antifungals may require dose adjustments.
Although the renal clearance of NOACs vary, patients with renal impairment may require dose reduction to avoid increased plasma concentrations of NOACs [ 4, 90– 92].
Individual patients may require doses to be adjusted by more than a factor of 2 to achieve effective analgesia without adverse effects (See Table 2) [ 26].
Comparisons concerning the numbers of drugs that may require dose adjustments were done using the two-sided Friedman- or Wilcoxon-test, as appropriate.
The future strategies for therapy of malignancies in which both radiation and chemotherapy are employed may require dose modification or treatment planning to limit bone marrow toxicity.
