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Gould speculates that young neurons may require critically timed input signals from connecting cells--maybe in the form of learning--to survive.
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They also suggest that the upper level of the reference value for lactate in critically ill patients may require readjustment.
Critically ill patients may require interhospital transfer for specialist care or because of a lack of local ICU capacity.
Critically ill patients may require mechanical ventilatory support and short-term high-dose corticosteroid to treat some specific underlying disease processes.
If these studies confirm the value of relative hyperlactatemia, the reference value for lactate in critically ill patients may require adjustment.
Other subgroups of critically ill patients with neutropenia may require anti-Aspergillus prophylaxis on a case-by-case basis.
Serial measurement of SOFA score in critically ill patients may help to identify patients who may require more aggressive therapeutic intervention and to avoid complications.
There are many causes for a deranged coagulation in critically ill patients and each of these underlying disorders may require specific therapeutic or supportive management.
The TIPS procedure can be performed with conscious sedation in most patients, although children, critically ill or uncooperative patients, and those on artificial ventilation may require general anesthesia.
These points suggest that the one-size-fits-all dosing recommendations based only on CRRT prescription may not apply to all different types of critically ill patients, as they are a highly heterogeneous population that may require different doses.
Traditional techniques for estimation of this critically important property are often not as accurate as is required and may require extended compositional analyses to be conducted beforehand.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com