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These features may require alternative approaches in educational design in order to maximize learning for millennial students.
Critical illness may alter a patients PK behaviour [[2]] and therefore these patients may require alternative dosing regimens for optimal management [[3]].
Thus, tumors that do not depend on CDK4/6 for G1-S transition and/or can rescue CDK4/6 inhibition by the activity of other CDKs may require alternative approaches, including the use of compounds that affect cyclin D1 transcription or protein turnover and combination therapies that target multiple endpoints of cyclin D1 action simultaneously [50].
In various conditions, including the host, the transcription of genes not controlled by PlcR despite the binding of the regulator to the PlcR box may require alternative sigma factors, such as σB, σH, or ECF factors.
However, in light of the growing drug resistance to SP [37], [38], its continued use for IPTp may eventually be replaced by more effective alternative drugs which may require alternative dosing schedules.
Establishing function for some of these predicted transporters may require alternative genetic, biochemical, or physiological analyses.
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One in four subjects with HF in this study may require alternatives to written materials to assist them in understanding their disease and following through with self-care.
Unfortunately, we had too few cases to be able to detect any association between NAT1 and survival among only tamoxifen treated patients, but this finding warrants further investigation and suggests that the low expression of NAT1 among luminal M1 tumors may lead to tamoxifen resistance, and that these patients may hence require alternative treatment approaches.
Loss of activated ERK1/2 may not only relieve the associated inhibitory mechanisms in a direct manner but may also require alternative mitogenic signals to take over in UM metastasis.
Differences between groups may also require alternative preventive strategies for sub-groups of parents.
And we may require an alternative literary history before either group is fully willing to admit it.
More suggestions(16)
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may require tough
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com